Publications

Publication List (in chronological order)

Zone Electrophoresis in Open-Tubular Glass Capillaries: Preliminary Data on Performance, J.W.
Jorgenson, K.D. Lukacs, Journal of High Resolution Chromatography, 4, 230-231 (1981).

Zone Electrophoresis in Open-Tubular Glass Capillaries, J.W. Jorgenson, and K.D. Lukacs, Analytical
Chemistry, 53, 1298-1302 (1981).

High Resolution Separations Based on Electrophoresis and Electroosmosis, J.W. Jorgenson, and K.D.
Lukacs, Journal of Chromatography, 218, 209-216 (1981).

Free Zone Electrophoresis in Glass Capillaries, J.W. Jorgenson, and K.D. Lukacs, Clinical Chemistry,
27, 1551-1553 (1981).

Liquid Chromatography in Open-Tubular Columns: Theory of Column Optimization With Limited
Pressure and Analysis Time, and Fabrication of Chemically Bonded Reversed-Phase Columns on
Etched Borosilicate Glass Capillaries, J.W. Jorgenson, and E.J. Guthrie, Journal of Chromatography,
255, 335-348 (1983).

Transmission Near-Infrared Technique for Evaluation and Relative Quantitation of Surface Groups on
Silica, S.G. Bush, J.W. Jorgenson, M.L. Miller, and R.W. Linton, Journal of Chromatography, 260, 1-12
(1983).

Technique for Accurate Measurement of Capillary Lengths and Diameters, E.J. Guthrie, J.W. Jorgenson,
L.A. Knecht, and S.G. Bush, Journal of High Resolution Chromatography, 6, 566-567 (1983).
Capillary Zone Electrophoresis, J.W. Jorgenson, and K.D. Lukacs, Science, 222, 266-272 (1983).
Zone Electrophoresis in Open-Tubular Capillaries, J.W. Jorgenson, Trends in Analytical Chemistry, 3,
51-54 (1984).

On-Column Electrochemical Detector With a Single Graphite Fiber Electrode for Open-Tubular Liquid
Chromatography, L.A. Knecht, E.J. Guthrie, and J.W. Jorgenson, Analytical Chemistry, 56, 479-482
(1984).

On-Column Fluorescence Detector for Open-Tubular Capillary Liquid Chromatography, E.J. Guthrie,
and J.W. Jorgenson, Analytical Chemistry, 56, 483-486 (1984).

Trends in Analytical Scale Separations, J.W. Jorgenson, Science, 226, 254-261 (1984).

High Speed Zone Electrophoresis in Open-Tubular Fused Silica Capillaries, J.S. Green, J.W. Jorgenson,
Journal of High Resolution Chromatography, 7, 529-531 (1984).

On-Column UV Absorption Detector for Open-Tubular Capillary Zone Electrophoresis, Y. Walbroehl,
J.W. Jorgenson, Journal of Chromatography, 315, 135-143 (1984).

Possible Chemical Basis For Histocompatibility-Related Mating Preference in Mice, F.J. Schwende,
J.W. Jorgenson, M. Novotny, Journal of Chemical Ecology, 10, 1603-1615 (1984).

Identification of a Testosterone-Dependent Unique Volatile Constituent of Male Mouse Urine: 7-exoethyl-
5-methyl-6,8-dioxabicyclo(3.2.1)-3-octene, M. Novotny, F.J. Schwende, D. Wiesler, J.W.
Jorgenson, and M. Carmack, Experientia, 40, 217-219 (1984).

On-Column Helium-Cadmium Laser Fluorescence Detector for Open-Tubular Capillary Liquid
Chromatography, E.J. Guthrie, J.W. Jorgenson, and P.R. Dluzneski, Journal of Chromatographic
Science, 22, 171-176 (1984).

New Techniques for Liquid Chromatography in Open-Tubular Columns, J.W. Jorgenson, E.J. Guthrie,
R.L. StClaire III, P.R. Dluzneski, and L.A. Knecht, Journal of Pharmaceutical and Biomedical Analysis,
2, 191-196 (1984).

Correlation of Retention Behavior with Quantitative Surface Analysis of Octadecyl Bonded
Chromatographic Supports, M.L. Miller, R.W. Linton, S.G. Bush, and J.W. Jorgenson, Analytical
Chemistry, 56, 2204-2210 (1984).

Capillary Zone Electrophoresis, J.W. Jorgenson, K.D. Lukacs, in “Microcolumn Separations: Columns,
Instrumentation and Ancillary Techniques”, M. Novotny and D. Ishii (editors), Journal of
Chromatography Library; Vol. 30, Elsevier, pp. 121-131 (1985).

Peak Broadening in Open-Tubular Liquid Chromatography with Electroosmotic Flow, M. Martin, G.
Guiochon, Y. Walbroehl, and J.W. Jorgenson, Analytical Chemistry, 57, 559-561 (1985).

Characterization of an On-Column Electrochemical Detector for Open-Tubular Liquid Chromatography,
R.L. StClaire III, and J.W. Jorgenson, Journal of Chromatographic Science, 23, 186-191 (1985).

Capillary Zone Electrophoresis: Effect of Physical Parameters on Separation Efficiency and
Quantitation, K.D. Lukacs, and J.W. Jorgenson, Journal of High Resolution Chromatography, 8, 407-
411 (1985).

Variable Wavelength On-Column Fluorescence Detector for Open-Tubular Zone Electrophoresis, J.S.
Green, and J.W. Jorgenson, Journal of Chromatography, 352, 337-343 (1986).

Capillary Zone Electrophoresis of Neutral Organic Molecules by Solvophobic Association with
Tetraalkylammonium Ion, Y. Walbroehl, and J.W. Jorgenson, Analytical Chemistry, 58, 479-481
(1986).

Scanning On-Column Voltammetric Detector for Open-Tubular Liquid Chromatography, J.G. White,
R.L. StClaire III, and J.W. Jorgenson, Analytical Chemistry, 58, 293-298 (1986).

Electrophoresis, J.W. Jorgenson, Analytical Chemistry, 58, 743A-760A (1986).

Improvements in Scanning Voltammetric Detection for Open-Tubular Liquid Chromatography, J.G.
White, and J.W. Jorgenson, Analytical Chemistry, 58, 2992-2995 (1986).

Urinary Volatile Constituents of the House Mouse, Mus musculus, and Their Endocrine Dependency,
F.J. Schwende, D. Wiesler, J.W. Jorgenson, and M. Novotny, Journal of Chemical Ecology, 12, 277-296
(1986).

A Design for Direct Coupling of Open-Tubular Liquid Chromatography with Mass Spectrometry, J. de
Wit, C.E. Parker, J.W. Jorgenson and K.B. Tomer, Anal. Chem., 59, 2400 (1987).

A Photoionization Detector for Open Tubular Liquid Chromatography, J.S.M. de Wit and J.W.
Jorgenson, J. Chromatogr., 411, 201 (1987).

Overview of Electrophoresis, in “New Directions in Electrophoretic Methods”, ed. by J.W. Jorgenson
and M. Phillips, American Chemical Society, Washington, D.C., 1987, pp.1-19.

Capillary Zone Electrophoresis, in “New Directions in Electrophoretic Methods”, ed. by J.W. Jorgenson
and M. Phillips, American Chemical Society, Washington, D.C., 1987, pp. 182-198.

Fraction Collector for Capillary Zone Electrophoresis, D.J. Rose and J.W. Jorgenson, J. Chromatogr.,
438, 23-34 (1988).

Characterization and Automation of Sample Introduction Methods for Capillary Zone Electrophoresis,
D.J. Rose and J.W. Jorgenson, Anal. Chem., 60, 642-648 (1988).

Nano-Scale Separations and Biotechnology, J.W. Jorgenson, D.J. Rose, R.T. Kennedy, American
Laboratory, 20 (4), 32,34,36,38,40,41 (1988).

New Method for the Preparation of Small Diameter Columns with Polymeric Stationary Phases for
Open Tubular Liquid Chromatography, P.R. Dluzneski and J.W. Jorgenson, J. High Resol. Chromatogr.
Chromatogr. Commun., 11, 332-336 (1988).

Pneumatic Microsyringe for Use as an Injector in Open Tubular Liquid Chromatography and as a
Dispenser in Microanalysis, R.T. Kennedy and J.W. Jorgenson, Anal. Chem., 60, 1521-1524 (1988).

Chemical Analysis of Single Neurons by Open Tubular Liquid Chromatography, R.T. Kennedy, R.L. St
Claire III, J.G. White, and J.W. Jorgenson, Mikrochimica Acta, 1987 (II), 37-45 (1988).

Design of a Coaxial Fast Atom Bombardment Probe, J.S.M. de Wit, L.J. Deterding, M.A. Moseley, K.B.
Tomer, J.W. Jorgenson, Rapid Communications in Mass Spectrometry, 2, 100-104 (1988).

Open Tubular Liquid Chromatography and the Analysis of Single Neurons, J.W. Jorgenson, R.T.
Kennedy, R.L. St. Claire III, J.G. White, P.R. Dluzneski, and J.S.M. de Wit, J. Res. Nat. Bureau
Standards, 93 (3), 403-406 (1988).

Separation and Identification of Trifluralin Metabolites by Open Tubular Liquid
Chromatography/Negative Chemical Ionization Mass Spectrometry, J.S.M. de Wit, C.E. Parker, K.B.
Tomer and J.W. Jorgenson, Biomed. Env. Mass Spec., 17, 47-53 (1988).

Post-Capillary Fluorescence Detection in Capillary Zone Electrophoresis Using o-phthaldialdehyde,
D.J. Rose and J.W. Jorgenson, J. Chromatogr., 447, 117-131 (1988).

High Speed Capillary Zone Electrophoresis with Laser Induced Fluorescence Detection, B. Nickerson
and J.W. Jorgenson, J. High Res. Chromatogr. Chromatogr. Commun., 11, 533-534 (1988).

High Sensitivity Laser Induced Fluorescence Detection in Capillary Zone Electrophoresis, B.Nickerson
and J.W. Jorgenson, J. High Resolut. Chromatogr. Chromatogr. Commun., 11, 878-881 (1988).

Determination of Low Nanogram Levels of Pesticides and Herbicides by Open Tubular Liquid
Chromatography (EI/CI) Mass Spectrometry, M.A. Moseley, J.S.M. de Wit, C.E. Parker, K.B. Tomer
and J.W. Jorgenson, in Proceedings of the 11th Annual Environmental Protection Agency Conference
on the Analysis of Pollutants in the Environment, Norfolk, VA, May 1988.

Characterization of the Direct Probe Open-Tubular Liquid Chromatography/Mass Spectrometry
Interface Parameters, J.S.M. de Wit, K.B. Tomer and J.W. Jorgenson, J. Chromatogr., 462, 365-375
(1989).

Capillary Zone Electrophoresis for the Determination of Electrophoretic Mobilities and Diffusion
Coefficients of Proteins, Y. Walbroehl and J.W. Jorgenson, J. Microcol. Sep., 1, 41-45 (1989).

Quantitative Analysis of Individual Neurons by Open Tubular Liquid Chromatography with
Voltammetric detection, R.T. Kennedy and J.W. Jorgenson, Anal. Chem., 61, 436-441 (1989).

Analysis of NDA-Labeled Amino Acids by Open Tubular Liquid Chromatography with Electrochemical
Detection, M.D. Oates and J.W. Jorgenson, Anal. Chem., 61, 432-435 (1989).

Separation of Dansylated Methylamine and Dansylated Methyl-D3-Amine by Micellar Electrokinetic
Capillary Chromatography with Methanol Modified Mobile Phase, M.M. Bushey and J.W. Jorgenson,
Anal. Chem., 61, 491-493 (1989).

Optimization of a Coaxial Continuous Flow Fast Atom Bombardment Interface Between Capillary
Liquid Chromatography and Magnetic Sector Mass Spectrometry for the Analysis of Biomolecules,
M.A. Moseley, L.J. Deterding, J.S.M. de Wit, K.B. Tomer, R.T. Kennedy and J.W. Jorgenson, Anal.
Chem., 61, 1577-1584 (1989).

Capillary Zone Electrophoresis/Fast-Atom Bombardment Mass Spectrometry: Design of an On-Line
Continuous Flow Interface, M.A. Moseley, L.J. Deterding, K.B. Tomer and J.W. Jorgenson, Rapid
Communications in Mass Spectrometry, 3, 87-93 (1989).

Effects of Methanol Modified Mobile Phase on the Separation of Isotopically Substituted Compounds
by Micellar Electrokinetic Capillary Chromatography, M.M. Bushey and J.W. Jorgenson, Journal of
Microcolumn Separations, 1, 125-130 (1989).

Chemical Phenomena in Solid State Voltammetry in Polymer Solvents, L. Geng, R.A. Reed, M.-H.
Kim, T.T. Wooster, B.N. Oliver, J. Egekeze, R.T. Kennedy, J.W. Jorgenson, J.F. Parcher and R.W.
Murray, J. Amer. Chem. Soc., 111, 1614 (1989).

Microcolumn Separations and the Analysis of Single Cells, R.T. Kennedy, M.D. Oates, B.R. Cooper, B.
Nickerson and J.W. Jorgenson, Science, 246, 57 (1989).

Voltammetric Detection with Gradient Elution for Open Tubular Liquid Chromatography, M.D. Oates
and J.W. Jorgenson, Anal. Chem., 61, 1977 (1989).

Preparation and Evaluation of Packed Capillary Liquid Chromatography Columns with Inner Diameters
from 20 to 50 μm, R.T. Kennedy and J.W. Jorgenson, Anal. Chem., 61, 1128-1135 (1989).

Minimizing Adsorption of Proteins to Fused Silica in Capillary Zone Electrophoresis via the Addition of
Alkali Metal Salts to the Buffers, J.S. Green and J.W. Jorgenson, J. Chromatogr., 478, 63-70 (1989).

Characterization of a Post Column Reaction-Laser Induced Fluorescence Detector for Capillary Zone
Electrophoresis, B. Nickerson and J.W. Jorgenson, J. Chromatogr., 480, 157-168 (1989).

Capillary Electrophoresis of Proteins in Buffers Containing High Concentrations of Zwitterionic Salts,
M.M. Bushey and J.W. Jorgenson, J. Chromatogr., 480, 301-310 (1989).

Coupling of Capillary Zone Electrophoresis and Capillary Liquid Chromatography with Coaxial
Continuous Flow Fast Atom Bombardment Tandem Sector Mass Spectrometry, M.A. Moseley, L.J.
Deterding, K.B. Tomer and J.W. Jorgenson, J. Chromatogr., 480, 197-209 (1989).

A Comparison of OTLC/MS and DLI-LC/MS for the Analysis of Metribuzin and its Metabolites in
Plant Tissue and Water Samples, B.H. Escoffier, C.E. Parker, T.C. Mester, J.S.M. de Wit, F.T. Corbin,
J.W. Jorgenson and K.B. Tomer, J. Chromatogr., 474, 301-316 (1989).

Coaxial Continuous Flow Fast Atom Bombardment in Conjunction With Tandem Mass Spectrometry
For The Analysis of Biomolecules, L.J. Deterding, M.A. Moseley, K.B. Tomer and J.W. Jorgenson,
Anal. Chem., 61, 2504-2511 (1989).

Design of a Variable Wavelength UV Absorption Detector for On-Column Detection in Capillary
Electrophoresis, and Comparison of its Performance to a Fixed Wavelength UV Absorption Detector,
J.S. Green and J.W. Jorgenson, J. Liq. Chromatogr., 12, 2527-2561 (1989).

Confirmation and Application of Transmission Near Infrared Absorption Technique for Absolute
Quantitation of Functional Groups on Silica Gel, S.G. Bush and J.W. Jorgenson, J. Chromatogr., 503,
69-91 (1990).

Automated Instrument for Comprehensive Two-Dimensional High- Performance Liquid
Chromatography of Proteins, M.M. Bushey and J.W. Jorgenson, Anal. Chem., 62, 161-167 (1990).

Quantitative Amino Acid Analysis of Individual Snail Neurons by Open Tubular Liquid
Chromatography, M.D. Oates, B.R. Cooper, and J.W. Jorgenson, Anal. Chem., 62, 1573-1577 (1990).

Quantitative Amino Acid Analysis of Subnanogram Levels of Protein by Open Tubular Liquid
Chromatography, M.D. Oates and J.W. Jorgenson, Anal. Chem., 62, 1577-1580 (1990).

Modification of Lysine Residues in Proteins to Improve Their Recovery When Using Derivatizing
Reagents, M.D. Oates and J.W. Jorgenson, Anal. Chem., 62, 2056-2058 (1990).

Efficiency of Packed Microcolumns Compared to Large Bore Packed Columns in Size Exclusion
Chromatography, R.T. Kennedy and J.W. Jorgenson, J. Microcolumn Separations, 2, 120-126 (1990).

Automated Instrument for Comprehensive Two-Dimensional High Performance Liquid
Chromatography-Capillary Zone Electrophoresis, M.M. Bushey and J.W. Jorgenson, Anal. Chem., 62,
978-984 (1990).

A Comparison of Tryptic Digests of Bovine and Equine Cytochrome C by Comprehensive Reversed
Phase HPLC-CE, M.M. Bushey and J.W. Jorgenson, J. Microcol. Sep., 2, 293-299 (1990).

Continuous Flow FAB with Packed Micro-Columns: A Comparison of Precolumn vs. Coaxial Matrix
Delivery, S. Pleasance, P. Thibault, M.A. Moseley, L.J. Deterding, K.B. Tomer and J.W. Jorgenson, J.
Amer. Soc. Mass Spectrom., 1, 312 (1990).

Capillary Zone Electrophoresis/Mass Spectrometry Using a Coaxial Continuous Flow Fast Atom
Bombardment Interface, M.A. Moseley, L.J. Deterding, K.B. Tomer, and J.W. Jorgenson, J.
Chromatogr., 516, 167 (1990).

Protein and Peptide Sequence Analysis by Tandem Mass Spectrometry in Combination with Either
Capillary Electrophoresis or Micro-capillary HPLC, D.F. Hunt, J. Shabanowitz, M.A. Moseley, A.L.
McCormack, H. Michel, P.A. Martino, K.B. Tomer and J.W. Jorgenson, in Proceedings of the 8th
International Conference on Protein Sequence Analysis, Elsevier, New York, New York, 1990.

On-Column Sample Gating for High-Speed Capillary Zone Electrophoresis, C.A. Monnig and J.W.
Jorgenson, Anal. Chem., 63, 802-807 (1991).

Sample Gating in Open Tubular and Packed Capillaries for High-Speed Liquid Chromatography, C.A.
Monnig, D.M. Dohmeier and J.W. Jorgenson, Anal. Chem., 63, 807-810 (1991).

Determination of Bioactive Peptides by Capillary Zone Electrophoresis/Mass Spectrometry, M.A.
Moseley, L.J. Deterding, K.B. Tomer, and J.W. Jorgenson, Anal. Chem., 63, 109-114 (1991).

Nanoscale Packed-Capillary Liquid Chromatography Coupled with Mass Spectrometry Using a Coaxial
Continuous-Flow Fast Atom Bombardment Interface, M.A. Moseley, L.J. Deterding, K.B. Tomer and
J.W. Jorgenson, Anal. Chem., 63, 1467-1473 (1991).

Preparation of Reversed Phase Open Tubular LC Columns from Borosilicate Glass, R.L. St Claire, D.M.
Dohmeier and J.W. Jorgenson, J. Microcolumn Sep., 3, 303-309 (1991).

Evaluation of Reversed-Phase Etched Borosilicate Glass Capillary Columns in Open Tubular Liquid
Chromatography, D.M. Dohmeier and J.W. Jorgenson, J. Microcolumn Sep., 3, 311-317 (1991).

Nanoscale Separations Combined with Tandem Mass Spectrometry, L.J. Deterding, M.A. Moseley,
K.B. Tomer, and J.W. Jorgenson, J. Chromatogr., 554, 73 (1991).

Nanoscale Separations: Capillary Liquid Chromatography/Mass Spectrometry and Capillary Zone
Electrophoresis/Mass Spectrometry for the Determination of Peptides and Proteins, L.J. Deterding,
M.A. Moseley, K.B. Tomer, and J.W. Jorgenson, J. Chromatogr., 554, 329 (1991).

Mass Spectrometric Methods for Protein and Peptide Sequence Analysis, D.F. Hunt, J.E. Alexander,
A.L. McCormack, P.A. Martino, H. Michel, J. Shabanowitz, N. Sherman, M.A. Moseley, J.W.
Jorgenson, and K.B. Tomer, in Techniques in Protein Chemistry II, J.J. Villafranca ed., Academic Press,
San Diego, CA, 1991.

Quantitative Determination of Catecholamines in Individual Bovine Adrenomedullary Cells by
Reversed Phase Microcolumn Liquid Chromatography with Electrochemical Detection, B.R. Cooper,
J.A. Jankowski, D.J. Leszczyszyn, R.M. Wightman and J.W. Jorgenson, Anal. Chem., 64, 691-694
(1992).

Direct Observation of Epinephrine and Norepinephrine Co-secretion from Individual Adrenal Medullary
Chromaffin Cells, E.L. Ciolkowski, B.R. Cooper, J.A. Jankowski, J.W. Jorgenson and R.M. Wightman,
J. Amer. Chem. Soc., 114, 2815-2821 (1992).

Detection in Microcolumn Liquid Chromatography, J.W. Jorgenson and J. de Wit, in “Detectors for
Capillary Chromatography”, ed. by H.H. Hill and D. McMinn, Vol. 121 in Chemical Analysis Series,
Wiley, 1992, Chapter 15 (pp. 395-425).

Optimization of Capillary Zone Electrophoresis/Electrospray Ionization Parameters for the Mass
Spectrometry and Tandem Mass Spectrometry Analysis of Peptides, M.A. Moseley, J. Shabanowitz,
D.F. Hunt, K.B. Tomer and J.W. Jorgenson, J. Amer. Soc. Mass Spectrom., 3, 289-300 (1992).
Capillary Electrophoresis: An Introduction, J.W. Jorgenson, Methods, A Companion to Methods in
Enzymology, 4, 179-190 (1992).

Median Filtering for Removal of Low Frequency Background Drift, A.W. Moore and J.W. Jorgenson,
Analytical Chemistry, 65, 188-191 (1993).

Two Dimensional Protein Separation by Microcolumn Size Exclusion Chromatography-Capillary Zone
Electrophoresis, A.V. Lemmo and J.W. Jorgenson, J. Chromatogr, 633, 213-220 (1993).
Rapid Scan Microvoltammetric Detection for Liquid Chromatography, J.G. White, A.L. Soli and J.W.
Jorgenson, J. Liq. Chromatogr., 16, 1489-1496 (1993).

Two Dimensional Separations of Peptides and Proteins by Comprehensive Liquid Chromatography-
Capillary Electrophoresis, J.P. Larmann Jr., A.V. Lemmo, A.W. Moore Jr., and J. W. Jorgenson,
Electrophoresis, 14, 439-447 (1993).

Transverse Flow Gating Interface for the Coupling of Microcolumn LC with CZE in a Comprehensive
Two Dimensional System, A.V. Lemmo and J.W. Jorgenson, Analytical Chemistry, 65, 1576-1581
(1993).

Preparation and Evaluation of an On-Line Preconcentrator for Capillary Electrophoresis, A.M. Hoyt, Jr.,
S.C. Beale, J.P. Larmann, Jr., and J.W. Jorgenson, J. Microcol. Sep., 5, 325-330 (1993).

Study of Zone Broadening in Optically-Gated High Speed Capillary Electrophoresis, A. W. Moore, Jr.,
and J. W. Jorgenson, Analytical Chemistry, 65, 3550-3560 (1993).

Quantitation of Epinephrine and Norepinephrine Secretion from Individual Adrenal Medullary Cells by
Microcolumn Liquid Chromatography, B.R. Cooper, R.M. Wightman and J.W. Jorgenson, J.
Chromatogr. B: Biomed. Appl., 653, 25-34 (1994).

Flow Counterbalanced Capillary Electrophoresis, C.T. Culbertson and J.W. Jorgenson, Analytical
Chemistry, 66, 955-962 (1994).

Electrospray-Condensation Particle Counter: A Molecule Counting LC Detector for Macromolecules,
K.C. Lewis, D.M. Dohmeier, J.W. Jorgenson, S.L. Kaufman, F. Zarrin, and F.D. Dorman, Analytical
Chemistry, 66, 2285-2292 (1994).

Separation of Nanoliter Samples of Biological Amines by a Comprehensive Two Dimensional
Microcolumn Liquid Chromatography System, L.A. Holland and J.W. Jorgenson, Analytical Chemistry,
67, 3275-3283 (1995).

Rapid Comprehensive Two-Dimensional Separations of Peptides via RPLC-Optically Gated Capillary
Zone Electrophoresis, A.W. Moore and J.W. Jorgenson, Analytical Chemistry, 67, 3448-3455 (1995).

Comprehensive Three Dimensional Separation of Peptides Using Size Exclusion Chromatography-
Reversed Phase Liquid Chromatography-Optically Gated Capillary Zone Electrophoresis, A.W. Moore
and J.W. Jorgenson, Analytical Chemistry, 67, 3456-3463 (1995).

Resolution of Cis and Trans Isomers of Peptides Containing Proline Using Capillary Zone
Electrophoresis, A.W. Moore and J.W. Jorgenson, Analytical Chemistry, 67, 3464-3475 (1995).

Electrochemical Detection of Histamine and 5-Hydroxytryptamine at Isolated Mast Cells, K. Pihel, S.
Hsieh, J.W. Jorgenson and R.M. Wightman, Analytical Chemistry, 67, 4514-4521 (1995).

Preparation and Evaluation of Slurry Packed Liquid Chromatography Microcolumns with Inner
Diameters from 12 to 33 Microns, S. Hsieh and J.W. Jorgenson, Analytical Chemistry, 68, 1212-1217
(1996).

Two Dimensional Liquid Chromatography-Capillary Electrophoresis Techniques for Analysis of
Proteins and Peptides, A.W. Moore, J.P. Larmann, Jr., A.V. Lemmo and J.W. Jorgenson, Methods in
Enzymology, Vol. 270, Part A, 401-419 (1996).

“Extraction and Gas Chromatographic Determination of Ethanol in Beverages”, N.J. Pienta, J.W.
Jorgenson, and R.M. Forbis, Chem. Educator, 1 (5): S 1430-4171(96)05066-9. (available at URL:

http://journals.springer-ny.com/chedr).

“Capillary Zone Electrophoresis with Electrospray Condensation Particle Counting Detection”, K.C.
Lewis, J.W. Jorgenson, S.L. Kaufman, J. Capillary Electrophoresis, 3 (5), 229-235 (1996).

“Ultra High Pressure Reversed Phase Liquid Chromatography in Packed Capillary Columns”, J.E.
MacNair, K.C. Lewis, and J.W. Jorgenson, Anal. Chem., 69, 983-989 (1997).

“Evaluation of Proteolytically Released Carbohydrate-Containing Peptides of Bovine Prothrombin
Fragment 1 Using Electrospray Ionization Mass Spectrometry and Capillary Electrophoresis”, K. R.
Birdwell, T. L. Austell, R. S. Black, J. W. Jorgenson, and R. G. Hiskey, J. Liq. Chromatogr. Relat.
Technol., 20, 987-1004 (1997).

“Comprehensive On-Line LC/LC/MS of Proteins”, by G.J. Opiteck, K.C. Lewis, J.W. Jorgenson, and
R.J. Anderegg, Analytical Chemistry, 69, 1518-1524 (1997).

“Two Dimensional SEC/RPLC Coupled to Mass Spectrometry for the Analysis of Peptides”, by G.J.
Opiteck, J.W. Jorgenson, and R.J. Anderegg, Analytical Chemistry, 69, 2283-2291 (1997).
“Comprehensive On-Line RPLC-CZE-MS of Peptides”, by K.C. Lewis, G.J. Opiteck, D.M. Sheely, and
J.W. Jorgenson, J. Amer. Soc. Mass Spectr., 8, 495-500 (1997).

“Counting Integral Numbers of gamma-Carboxyglutamic Acids per Peptide Chain Using Capillary
Electrophoresis”, by R.S. Black, G.M. Adams, J.W. Jorgenson, and R.G. Hiskey, J. Liq. Chromatogr.
Relat. Technol., 20, 2009-2021 (1997).

“A New Transverse Flow Gating Interface for the Coupling of Microcolumn LC with CZE in a
Comprehensive Two-Dimensional System”, by T.F. Hooker and J.W. Jorgenson, Analytical Chemistry,
69, 4134-4142 (1997).

“Rapid Separation and Characterization of Protein and Peptide Mixtures Using 1.5 μm Diameter Non-
Porous Silica in Packed Capillary LC/MS, J.E. MacNair, G.J. Opiteck, J.W. Jorgenson, and M. Arthur
Moseley, Rapid Commun. Mass Spectr., 11, 1279-1285 (1997).

“Determination of Enzyme Activity in Single Bovine Adrenal Medullary Cells by Separation of
Isotopically-Labeled Catecholamines”, by S. Hsieh and J.W. Jorgenson, Analytical Chemistry, 69, 3907-
3914 (1997).

“Sensitive Analysis of [D-PEN2,5] Enkephalin in Rat Serum with Capillary Electrophoresis and Laser-
Induced Fluorescence Detection”, C. Chen, D. Jeffery, J.W. Jorgenson, M.A. Moseley and G.M.
Pollack, J. Chromatogr. B, Biomed, Appl., 697, 149-162 (1997).

“A Multidimensional Approach to Protein Characterization”, by R.J. Anderegg, D.S. Wagner, R.K.
Blackburn, G.J. Opiteck, and J.W. Jorgenson, Journal of Protein Chemistry, 16, 523-526 (1997).
“Two-Dimensional Liquid Chromatography-Capillary Electrophoresis”, by D.J. Jeffery, T.F. Hooker,
and J.W. Jorgenson, Chapter 27 in “Handbook of Capillary Electrophoresis, Second Edition”, ed. by J.
Landers, CRC Press, pp 765-790, 1997.

“Quantal Corelease of Histamine and 5-Hydroxytryptamine from Mast Cells and the Effects of Prior
Incubation”, K. Pihel, S. Hsieh, J.W. Jorgenson and R.M. Wightman, Biochemistry, 37, 1046-1052
(1998).

“Separation and Identification of Peptides in Single Neurons by Microcolumn Liquid Chromatography-
Matrix Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry and Post Source Decay
Analysis”, by S. Hsieh, K. Dreisewerd, R.C. van den Schors, C.R. Jimenez, J. Stahl-Zeng, R.C. Baden,
F. Hillenkamp, J.W. Jorgenson, W.P.M. Geraerts, and K.W. Li, Analytical Chemistry, 70, 1847-1852
(1998).

“Comprehensive Two Dimensional HPLC for the Isolation of Overexpressed Proteins and Proteome
Mapping”, G.J. Opiteck, S.M. Ramirez, J.W. Jorgenson, M.A. Moseley III, Anal. Biochem, 258, 349-
361 (1998).

“Two-Dimensional Microcolumn HPLC Coupled to a Single Quadrupole Mass Spectrometer for the
Elucidation of Sequence Tags and Peptide Mapping”, by G.J. Opiteck, J.W. Jorgenson, M.A. Moseley
III, and R.J. Anderegg, Journal of Microcolumn Separations, 10, 365-375 (1998).

“Lowering the UV Absorbance Detection Limit in Capillary Zone Electrophoresis Using a Single Linear
Photodiode Array Detector”, by C.T. Culbertson and J.W. Jorgenson, Analytical Chemistry, 70, 2629-
2638 (1998).

“Pressure-Induced Retention Variations in Reversed-Phase Alternate-Pumping Recycle
Chromatography”, by K. Lan and J.W. Jorgenson, Anal. Chem., 70, 2773-2782 (1998).

“Capillary Reverse Phase HPLC with Electrospray Condensation Particle Counting Detection”, K.C.
Lewis, J.W. Jorgenson, S.L. Kaufman, J.W. Skogen, J. Microcolumn Separations, 10, 467-471 (1998).

“Two-Dimensional Separations in High Performance Capillary Eectrophoresis”, by T.F. Hooker, D.J.
Jeffery, and J.W. Jorgenson, Chapter 17 in “High-Performance Capillary Electrophoresis : Theory,
Techniques, and Applications”, edited by M. G. Khaledi, John Wiley & Sons, New York, 1998.

“Increasing the Resolving Power of Capillary Electrophoresis Through Electroosmotic Flow Control
Using Radial Fields”, by C.T. Culbertson and J.W. Jorgenson, Journal of Microcolumn Separations, 11,
167-174 (1999).

“Separation of Fluorescently Derivatized Perdeuterated Isotopomers of Phenylalanine Using Micellar
Electrokinetic Chromatography and Flow-Counterbalanced Micellar Electrokinetic Chromatography”,
by C.T. Culbertson and J.W. Jorgenson, Journal of Microcolumn Separations, , 11, 175-183 (1999).

“Ultra High Pressure Reversed-Phase Liquid Chromatography: Isocratic and Gradient Elution Using
Columns Packed with 1.0 μm Particles”, by John MacNair, Kamlesh Patel, and J.W. Jorgenson,
Analytical Chemistry, 71, 700-708 (1999).

“Automated Measurement of Peak Widths for the Objective Determination of Peak Capacity Factor in
Complex Chromatograms”, by Kevin Lan and J.W. Jorgenson, Analytical Chemistry, 71, 709-714
(1999).

“Ultra-High Voltage Capillary Zone Electrophoresis”, by K.M. Hutterer and J.W. Jorgenson, Analytical
Chemistry, 71, 1293-1297 (1999).

“Synchronous Cyclic Capillary Electrophoresis Using Conventional Capillaries: System Design and
Preliminary Results”, by J. Zhao, T. Hooker and J.W. Jorgenson, Journal of Microcolumn Separations,
11, 431-437 (1999).

“Application of Synchronous Cyclic Capillary Electrophoresis: Isotopic and Chiral Separations”, by J.
Zhao and J.W. Jorgenson, Journal of Microcolumn Separations, 11, 439-449 (1999).

“Lowering the UV Absorbance Detection Limit and Increasing the Sensitivity of Capillary Zone
Electrophoresis Using a Dual Linear Photodiode Array Detector and Signal Averaging”, by C.T.
Culbertson and J.W Jorgenson, J. Microcolumn Separations, 11, 652-662 (1999).

“Theoretical Investigation of the Spatial Progression of Temporal Statistical Moments in Linear
Chromatography“, by Kevin Lan and James W. Jorgenson, Analytical Chemistry, 72, 1555-1563 (2000).

“Characterization of a Comprehensive Two-Dimensional Anion Exchange-Perfusive Reversed Phase
Liquid Chromatography System for Improved Separation of Peptides”, by L.A. Holland and J.W.
Jorgenson, Journal of Microcolumn Separations, 12 (6), 371-377 (2000).

“High Resolution of Oligosaccharide Mixtures by Ultra-High Voltage Micellar Electrokinetic Capillary
Chromatography”, by K.M. Hutterer, H. Birrell, P. Camilleri and J. W. Jorgenson, Journal of
Chromatography, Part B, 745, 365-372 (2000).

“Spatial and Temporal Progression of Spatial Statistical Moments in Linear Chromatography,” by Kevin
Lan and James W. Jorgenson, Journal of Chromatography A, 905, 47-57 (2001).

“Very High Pressure Gradient LC/MS/MS”, Tolley, Luke; Jorgenson, James W.; and Moseley, M.
Arthur, Analytical Chemistry (2001), 73(13), 2985-2991.

“A Hybrid of Exponential and Gaussian Functions as a Model of Asymmetric Chromatographic Peaks”,
by Kevin Lan and James W. Jorgenson, Journal of Chromatography, Part A, 915, 1-13 (2001).

“HPLC of Monolayer Protected Gold Nanoclusters”, by Victoria L. Jimenez, Michael C. Leopold,
Carolyn Mazzitelli, James W. Jorgenson, and Royce W. Murray, Analytical Chemistry, 75, 199-206
(2003).

“The Use of Micrometer-sized Particles in Ultrahigh Pressure Liquid Chromatography”, Jerkovich,
Anton D., Mellors, J. Scott, Jorgenson, James W., LC-GC North America, 21 (7), pp. 600, 604, 606,
608, 610, (2003) (also published in: LC-GC Europe, 16, pp. 20-23, 2003).

“Multidimensional LC-LC and LC-CE for high resolution separations of biological molecules”, Charles
R. Evans and James W. Jorgenson, Analytical and Bioanalytical Chemistry, 378 (8), 1952-1961 (2004).

“The Use of 1.5 micron Porous Ethyl-Bridged Hybrid Particles as a Stationary Phase Support for
Reversed-Phase Ultra-High Pressure Liquid Chromatography”, J. Scott Mellors, and James W.
Jorgenson, Analytical Chemistry, 76, 5441-5450 (2004).

“In-depth Characterization of Slurry Packed Capillary Columns with 1.0 micron Nonporous Particles
Using Reversed Phase Isocratic Ultra-High Pressure Liquid Chromatography”, Kamlesh D. Patel, Anton
D. Jerkovich, Jason C. Link and James W. Jorgenson, Analytical Chemistry, 76, 5777-5786 (2004).

“Investigation of Electrospray Ionization and Electrostatic Focusing Devices Using a Three-
Dimensional Electrospray Current Density Profiler”, J. Will Thompson, John W. Eschelbach, Richard T.
Wilburn, and James W. Jorgenson, Journal of the American Society for Mass Spectrometry, 16, (3),
312-323 (2005).

“Separation of Hyaluronic Acid by Ultrahigh-Voltage Capillary Gel Electrophoresis”, Katariina M.
Hutterer and James W. Jorgenson, Electrophoresis, 26 (10), 2027-2033 (2005).

“Linear Velocity Surge Caused by Mobile-Phase Compression as a Source of Band Broadening in
Isocratic Ultrahigh-Pressure Liquid Chromatography”, A. Jerkovich, S. Mellors, J.W. Thompson, and
J.W. Jorgenson, Analytical Chemistry, 77, 6292-6299 (2005).

“Flow Counterbalanced Capillary Electrophoresis Using Packed Capillary Columns: Resolution of
Enantiomers and Isotopomers”, Wm. Hampton Henley, Richard T. Wilburn, Andrew M. Crouch, and
James W. Jorgenson, Analytical Chemistry, 77, 7024-7031 (2005).

“Expanded Electrical Model of a Contactless Conductivity Detector: Development and Verification”,
Stephen Johnston, Keith E. Fadgen, Luke T. Tolley, James W. Jorgenson, Journal of Chromatography
A, 1094, 148-157 (2005).

“Improved Protein Recovery in Reversed-Phase Liquid Chromatography by the Use of Ultrahigh
Pressures”, John Eschelbach and J.W. Jorgenson, Analytical Chemistry, 78, 1697-1706 (2006).

“Recent Advances in Ultrahigh-Pressure Liquid Chromatography”, J.W. Thompson, J.S. Mellors, J.W.
Eschelbach and J.W. Jorgenson, LC/GC North America, 24 (S4), pp. 16, 18, 19, 20 (2006).

“Development of a Conductivity-Based Photothermal Absorbance Detector for Capillary Separations”,
S. E. Johnston, K. E. Fadgen, and J. W. Jorgenson, Analytical Chemistry, 78, 5309-5315 (2006).

“Viscosity Measurements of Methanol-Water and Acetonitrile-Water Mixtures at Pressures up to 3500
bar Using a Novel Capillary Time-of-Flight Viscometer”, Joseph Will Thompson, Theodore J Kaiser,
James W Jorgenson, J. Chromatogr. A, 1134, 201-209 (2006).

“Extreme Resolution in Capillary Electrophoresis: UHVCE, FCCE and SCCE”, Wm. Hampton Henley,
James W. Jorgenson, pp 723-760, in Handbook of Capillary and Microchip Electrophoresis and
Associated Microtechniques, 3rd Ed., edited by James P. Landers, CRC Press, Taylor and Francis Group,
Boca Raton, FL (2008).

“Deracemization of a Dynamic Combinatorial Library Induced by (−)-Cytidine and (−)-2-Thiocytidine”,
Mee-Kyung Chung, Christine M. Hebling, James W. Jorgenson, Kay Severin, Stephen J. Lee, and
Michel R. Gagne, J. Am. Chem. Soc., 130 (35), pp 11819–11827 (2008).

“Capillary-Based Instrument for the Simultaneous Measurement of Solution Viscosity and Solute
Diffusion Coefficient at Pressures up to 2000 bar and Implications for Ultrahigh Pressure Liquid
Chromatography”, Theodore J. Kaiser, J. Will Thompson, J. Scott Mellors, and James W. Jorgenson,
Analytical Chemistry, 81, pp 2860–2868 (2009).

“Hydrodynamic Chromatography for the Size Classification and Purification of Micron and Sub-micron
Sized Packing Materials”, J. Will Thompson, Rachel A. Lieberman and James W. Jorgenson, J.
Chromatography A, 1216 7732–7738 (2009).

“Development of a Photothermal Absorbance Detector for Use with Microfluidic Devices”, Patty J.
Dennis, Erin R. Ferguson, Jean Pierre Alarie, J. Michael Ramsey and James W. Jorgenson, Analytical
Chemistry, 82, 4063–4071 (2010).

“Conformational analysis of membrane proteins in phospholipid bilayer nanodiscs by
hydrogen exchange mass spectrometry”, Christine M. Hebling, Christopher R. Morgan, Darrel W.
Stafford, James W. Jorgenson, Kasper D. Rand and John R. Engen, Analytical Chem., 82, pp 5415–5419
(2010).

“Novel aspects of quantitation of immunogenic wheat gluten peptides by liquid chromatography–mass
spectrometry/mass spectrometry” Jennifer A. Sealey-Voyksner, Chaitan Khosla, Robert D. Voyksner,
James W. Jorgenson, Journal of Chromatography A, 1217, 4167–4183 (2010).

“Capillary Liquid Chromatography at Ultra High Pressures”, James W. Jorgenson, chapter in Annual
Review of Analytical Chemistry, Edward Yeung and Richard Zare, eds., Vol. 3, pp 129-150 (2010).

“Effect of Vitamin K-Dependent Protein Precursor Propeptide, Vitamin K Hydroquinone and
Glutamate Substrate Binding on the gamma-Glutamyl Carboxylase’s Structure and Function”, Shannon
L. Higgins-Gruber, Vasantha P. Mutucumarana, Pen-Jen Lin, James W. Jorgenson, Darrel W. Stafford,
and David L. Straight, J. Biol Chem., 285, 31502-31508 (2010).

“1.1 μm superficially porous particles for liquid chromatography. Part I: Synthesis and particle structure characterization”, Laura E. Blue and James W. Jorgenson, J. Chromatography A, 1218 7989-7995 (2011).

 

Patents, J. W. Jorgenson

“Coaxial Flow Post Capillary Mixing”, J.W. Jorgenson and D.J. Rose, U.S. Patent No. 4,936,974.

“Microelectrospray Method and Apparatus”, J.W. Jorgenson and D.M. Dohmeier, U.S. Patent No.
5,115,131.

“Two-Dimensional High-Performance Liquid Chromatography/Capillary Electrophoresis”, J.W.
Jorgenson and M.M. Bushey, U.S. Patent No. 5,131,998.

“Two-Dimensional High-Performance Liquid Chromatography/Capillary Electrophoresis”, J.W.
Jorgenson and M.M. Bushey, U.S. Patent No. 5,240,577.

“Method and Device for High Speed Separation of Complex Molecules”, J.W. Jorgenson and C.A.
Monnig, U.S. Patent No. 5,269,900.

“Two-Dimensional Separation System”, J.W. Jorgenson and A.V. Lemmo, U.S. Patent No. 5,389,221.

“Two-Dimensional Separation System”, J.W. Jorgenson and A.V. Lemmo, U.S. Patent No. 5,496,460.